Methemoglobinemia caused by dapsone overdose: Which treatment is best?
Ibrahim Toker, Murat Yesilaras, Feriyde Caliskan Tur, Rana Toktas
Department of Emergency Medicine, Tepecik Training and Education Hospital, Izmir, Turkey
Keywords: Dapsone overdose; Emergency medicine; Methemoglobinemia
Abstract
Increase of methemoglobin level is named as methemoglobinemia characterized by functional anemia and tissue hypoxia. Methemoglobinemia can be congenital, but acquired form are more often caused by various drugs and toxins. Methylene blue is the most effective antidote for acquired methemoglobinemia. When methylene blue is not available, alternative treatments such as ascorbic acid and hyperbaric oxygen can be useful. In this paper we presented a case of methomoglobinemia due to dapsone overdose.